The term "detectable signal" is a signal derived from non-invasive imaging techniques such as, but not limited to, positron emission tomography (PET).

The term "therapeutically effective amount" refers to at least the minimal dose, but less than a toxic dose, of an agent which is necessary to impart a therapeutic benefit to a subject. The term "epitope" or "antigenic determinant" refers to a site on an antigen (e.g., huCD40) to which an immunoglobulin or antibody speci***ally binds.
For example, a CD40 agonist and one or more additional antibodies (e.g., CTLA-4 and/or PD-1 and/or PD-L1 and/or LAG-3 blockade) can be effectively combined with chemotherapeutic regimes. I think I’m trans. Because we’re in such a moment now where transness is so much more in the fore, and yet I think butch was the first way to identify with as one who grew up thinking perhaps that you were a boy rather than a girl." "You know, there’s a lot of complaint among a lot of butches that butches are dying off, that we’re an endangered species.


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